NCG collects 1,400 cancer genes from different sources:
  • Cancer gene census (CGC)
  • High-throughput mutational screenings (HTMS) of cancer samples
  • Whole-genome sequencing (WGS) of cancer samples
For each cancer genes, NCG provides information on:
  • duplicability
  • orthology
  • evolutionary appearance
  • protein-protein interactions
  • miRNA-genes interactions
  • functional properties

Gene Search

Info  Search for a specific gene
Insert a gene identifier

Multiple queries
Select the type of identifier you are inserting NCG guess
Gene symbol (e.g. PTEN , use * for multiple genes)
Entrez GeneID (e.g. 5728)
RefSeq Protein Identifier (e.g. NP_000305)
Ensembl Protein Identifier (e.g. ENSP00000361021)

Search for cancer genes within a genomic region Chromosome: Start: End:

Browse Gene Lists

Info  Browse precompiled lists of cancer genes
All All cancer (1400)
CGC Futreal, Nature 2004 (447)
Santarius, Nature 2010 (77)
All CGC (501)
HTMS Barretina, Nature Genetics 2010 (21)
Chapman, Nature 2011 (10)
Dalgliesh, Nature 2010 (5)
Ding, Nature 2008 (26)
Greif, Leukemia 2011 (5)
Jiao, Science 2011 (7)
Jones, Nature 2008 (82)
Kan, Nature 2010 (112)
Parsons, Science 2008 (42)
Cancer Genome Atlas, Nature 2008 (8)
Wei, Nature Genetics 2011 (68)
Wood, Science 2007 (272)
All HTMS (578)
WGS Berger, Nature 2011 (88)
Chapman, Nature 2011 (10)
Clark, PLOS Genetics 2010 (60)
Ding, Nature 2010 (49)
Lee, Nature 2010 (16)
Ley, Nature 2008 (10)
Mardis, NEJM 2009 (12)
Pleasance, Nature 2010 (60)
Pleasance, Nature 2010 (62)
Shah, Nature 2009 (31)
Totoki, Nature Genetics 2011 (71)
All WGS (456)

Advanced Search

Info  Retrieve genes that share similar properties
Cancer Genes OR AND
All cancer (1400)
Futreal, Nature 2004 (447)
Santarius, Nature 2010 (77)
All CGC (501)
Barretina, Nature Genetics 2010 (21)
Chapman, Nature 2011 (10)
Dalgliesh, Nature 2010 (5)
Ding, Nature 2008 (26)
Greif, Leukemia 2011 (5)
Jiao, Science 2011 (7)
Jones, Nature 2008 (82)
Kan, Nature 2010 (112)
Parsons, Science 2008 (42)
Cancer Genome Atlas, Nature 2008 (8)
Wei, Nature Genetics 2011 (68)
Wood, Science 2007 (272)
All HTMS (578)
Berger, Nature 2011 (88)
Chapman, Nature 2011 (10)
Clark, PLOS Genetics 2010 (60)
Ding, Nature 2010 (49)
Lee, Nature 2010 (16)
Ley, Nature 2008 (10)
Mardis, NEJM 2009 (12)
Pleasance, Nature 2010 (60)
Pleasance, Nature 2010 (62)
Shah, Nature 2009 (31)
Totoki, Nature Genetics 2011 (71)
All WGS (456)
Cancer Types OR AND
All cancer types
amplified
breast
colorectal
epithelial cancer
glioblastoma
kidney
leukemia
liver
lung
melanoma
mesenchimal cancer
myeloma
ovarian
pancreas
prostate
sarcoma
dominant genes
recessive genes
other types of cancer
Duplicability No filter
Duplicable Genes
Singleton Genes

Function OR AND
No filter
Cell behavior
Cell cycle
DNA/RNA metabolism
Intracellular metabolism
Intracellular processes
Development
Regulation of intracellular processes
Signal transduction
Stress response
Transcription
Other

Appearance in Evolution No filter
Last Common Ancestor
Eukaryotes
Opistokonts
Metazoans
Vertebrates
Mammals
Primates

PIN No filter
Hubs
non-Hubs

miRNA/gene interactions

Info  Search for microRNAs or target genes
Insert a gene or microRNA identifier
Select the type of identifier you are inserting NCG guess
Target Gene (e.g. PTEN , 5728)
miRNA Identifier (e.g. miR-126* , hsa-mir-126)

Targets of miRNAs

Info Get the list of all cancer genes that are targets of miRNAs

Hosts of miRNAs

Info Get the list of all cancer genes that are hosts of miRNAs